Preparation of Controlled Release Particles by Suspension Spray Method Using Fluidized Bed Coater with Rotary Disk.

The preparation of the sustained release metformin hydrochloride microcapsules by the Wurster fluidized bed.

The main objective of this study was to prepare sustained release metformin hydrochloride microcapsules by the Wurster fluidized bed and to obtain the optimized coating process and formulation. Fine microcapsules without agglomeration were obtained in a continuous coating process with the atomization air pressure of 0.2Mpa and an appropriate coating speed temperature. With other design variable...

Effect of Process Variables on Growth Kinetics of Lactose Particles in a Wet Spray Fluidized Bed Granulator

Preparation and Characterization of Inorganic PCM Microcapsules by Fluidized Bed Method

The literature shows that inorganic phase change materials (PCM) have been very seldom microencapsulated, so this study aims to contribute to filling this research gap. Bischofite, a by-product from the non-metallic industry identified as having good potential to be used as inorganic PCM, was microencapsulated by means of a fluidized bed method with acrylic as polymer and chloroform as solvent,...

Simulation of Particles with Different Coefficient of Restitution in Fluid Bed Coater

Particle coating using fluid bed technology such as Wurster chamber is a common process in pharmaceutical technology. Coatings are used to achieve variety of functions, such as: taste masking, controlled release, increase of stability and others. Coating uniformity is one of the most important parameters of coated particles and can play an important role in the release of the active ingredient ...

Simulation of the Hydrodynamics Behavior in a Bubbling Fluidized Bed Reactor with Nano-Particles Using CFD Method

In this study hydrodynamics of a fluidized bed reactor with fumed silica nano particles was modeled using CFD method. Hydrodynamics parameters such as gas and solid velocity and void fraction have been investigated. The minimum fluidization velocity was around 0.0115 m/s at solids volume fraction of 0.0077. Fluidization process was involving a high expansion ratio of bed and without large bubbl...